SIBO Product Buyer’s Guide (updated May 2024)

Approved Science Siboprin Review



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Our research has shown that Approved Science created a science-based formula that contains high-quality ingredients. Siboprin contains Micro-Sci, a unique herbal complex with three of the most potent ingredients to combat SIBO, together with Caprylic acid and BioPerine® for optimal health benefits. We also like that Approved Science manufactures all of its products in an FDA and GMP recognized facility that complies with the standards for quality and purity outlined by the U.S. Phramacopeia
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Why do we recommend Approved Science Siboprin?

Main Benefits:

  • Helps to improve symptoms of SIBO in a natural, effective manner.
  • Contains Micro-Sci, a unique antimicrobial complex comprising three proven herbal extracts to combat SIBO: Oregano, Barberry, and Garlic.
  • Contains an impressive 500mg Oregano extract to kill off undesirable microbes in the small intestine.
  • Contains Caprylic acid which complements and supports the herbal extracts to aid in the restoration of a balanced gut microbiome.
  • Added BioPerine® improves the bioavailability of all the other ingredients for quicker, more effective results.
  • Targets both hydrogen- and methane-producing bacteria for comprehensive relief.
  • No preservatives, artificial colorings, hormones, or unnecessary ingredients that may dilute the efficacy of the product.

In addition to the above points, we found many supportive consumer reviews from users who had experienced excellent results, and the company’s customer service team offers first-rate support and help. Furthermore, it offers a solid 60-day money-back guarantee if customers are not satisfied with their results.


Siboprin stands out from the competition due to its unique combination of Oregano, Barberry, and Garlic extracts in a trademarked herbal complex called Micro-Sci. Unlike other formulations on the market, it incorporates all three herbs, each backed by clinical studies which highlight their individual properties and benefits. Moreover, Siboprin provides these extracts in highly effective dosages, with 500mg of Oregano, 400mg of Barberry and 180mg of Garlic. We were pleased to see that the Garlic extract is standardized to 0.2% Allicin, an exceptionally potent antimicrobial compound with demonstrated efficacy against not only bacteria but also fungi, viruses, and protozoa. Additionally, the Barberry extract is standardized to contain 5% Berberine, the most extensively studied compound in Barberry known for its remarkable antimicrobial effects. 

In addition to its powerful herbal combination, Siboprin further sets itself apart by including 300mg of Caprylic acid. Surprisingly, many other SIBO formulations lack this essential ingredient, despite its significance. Caprylic acid complements the herbal extracts in Siboprin by providing additional antimicrobial properties that specifically target harmful bacteria in the small intestine. This offers numerous benefits to individuals with SIBO, including its ability to disrupt biofilms, which are protective coatings that bacteria create to resist treatment. Furthermore, Caprylic acid helps rebalance the gut microbiota, supports digestion, and promotes overall gut health. By incorporating Caprylic acid, Siboprin offers a comprehensive approach that tackles SIBO from multiple angles.

In addition to the Micro-Sci herbal complex and the Caprylic acid powder, this product also contains BioPerine®, a patented bioavailability enhancer that increases nutrient absorption and utilization. This ingredient helps you to get the best out of every capsule. While many manufacturers don’t even consider this ingredient, we consider it to be a key factor in boosting the ranking of a supplement.

What we really like is that Siboprin is made by a company that consistently uses clinical studies as a benchmark for the dosage of all their health supplements. There is also a money-back guarantee which can be claimed by speaking to authentic customer service representatives rather than automated systems, to directly address their concerns and inquiries. There are so many products out there from manufacturers who do not commit themselves to such high standards, offering artificial alternatives and all sorts of extras inside their formulas.  It is a relief to be able to recommend a company that manufactures such a unique, well-researched SIBO supplement.

To summarize, Approved Science Siboprin uses top quality natural ingredients, provides awesome results, has a caring customer support team, and a great price. From what we saw, without a doubt, this is an extremely good product.

Quality Assurance

We were very happy to discover that Approved Science Siboprin is manufactured in an FDA-registered facility. Moreover, it is cGMP certified and complies with the US Pharmacopeia’s standards for quality and purity. This suggests that Approved Science takes what it does very seriously, and strives to keep its products safe, natural, and effective – a mentality that we totally appreciate.

Over the last few years, we understand how consumers have grown skeptical of health supplements. This simply comes down to shady companies providing ineffectual formulas that contain unrelated and useless ingredients, or that add fillers or binders to their products. The active ingredients are what deliver results, so when you see a long list of inactive ingredients, you should be wary. Often, these ingredients are not pure, or have not been tested for quality and have no scientific validity as to why they have been included in the formulas. Not only is this irresponsible, but often quite dangerous since there is frequently a lack of understanding when it comes to these ingredients. Truth being, there is absolutely no reason why anything artificial should be added. Natural and pure is the best. If the ingredients are in their natural form, they are less likely to cause side effects or negative interactions.


Approved Science Siboprin comes at an affordable price with some excellent multiple purchase deals, allowing you to benefit from big savings. Also, this company is staunchly against any auto-ship programs because they can be nearly impossible to cancel. This policy further supports the evidence that Approved Science is a top quality company.

Orders are shipped within 24 hours, with the exclusion of any orders placed on weekends and holidays. They are wrapped and sent in discreet packaging with no identifying marks on the outside, unlike other companies who often have embarrassing slogans or logos. Furthermore, this company provides a 60-day risk-free money-back guarantee. If you are not 100% happy with the results, you are able to return the product and receive a full refund. That shows Approved Science’s strong confidence in its product and we totally support that kind of guarantee.

In Conclusion

Approved Science Siboprin contains the optimal blend of ingredients which are clinically proven to make an effective SIBO supplement. It contains:

  • Oregano, Barberry, and Garlic: the most effective herbal extracts to combat SIBO.
  • 5% Berberine and 0.2% Allicin, powerful compounds to improve SIBO symptoms.
  • Caprylic acid for added antibacterial, antifungal, and anti-inflammatory properties.
  • BioPerine® for enhancing nutrient absorption and delivering faster results.
  • No unnecessary ingredients.

Of all the products that we reviewed, across all parameters, none compared to Approved Science Siboprin. This product complies with the high standards of the US Pharmacopeia, undergoes third-party testing, and is backed by comprehensive customer reviews that give us a great indication of how the product really works. If you are looking for a top quality formula backed by research and scientific data that is an effective, long-term solution to provide relief from SIBO, you would be hard pressed to find anything better than Approved Science Siboprin.

Approved Science Siboprin
Amy Myers MD Microb-Clear
Integrative Therapeutics Berberine Complex
Dr. Tobias Oregano & Caprylic Acid Blend
Oregano, Barberry & Garlic for antimicrobial properties 
500mg of Oregano to kill bacteria & fungus
Berberine and Allicin to tackle SIBO 
Caprylic acid to support good bacteria & reduce inflammation
Black Pepper extract to boost bioavailability 
Vegan friendly 
Third-party tested for purity
GMP certified
60-day money-back guarantee

FAQs about Approved Science Siboprin:

How does Approved Science Siboprin work?

An effective SIBO supplement works by targeting the underlying causes and symptoms associated with this condition. SIBO occurs when there is an overgrowth of bacteria in the small intestine, leading to various digestive symptoms such as bloating, gas, diarrhea, and abdominal pain. To address these issues, a high-quality SIBO supplement should contain ingredients with antimicrobial properties, such as Oregano, Berberine, and Garlic extracts, to reduce the overgrowth of bacteria and yeast in the small intestine. This helps to restore a healthier bacterial balance in the small intestine and promote a healthy gut environment.

The correct formula holds the key to success, so look for something that contains ingredients that work to kill unwanted bacteria and yeast in the small intestine, reduce inflammation, and promote a healthy gut microbiome. The formula should not be filled with ingredients that only look good on the label, but rather with ingredients that have been clinically proven to be effective and are backed by scientific research for optimum results. 

Do all SIBO supplements work in a similar way?

No, they do not. There are many companies that just ride the trends, producing inferior products with weak formulas in the wrong proportions. Many use incorrect ingredients, fillers, binders, or worse – ingredients that can affect desired results and even be dangerous.

What should I look for in an effective SIBO supplement?

  • It should contain Oregano, Barberry, and Garlic – 3 key herbs with proven antimicrobial properties to destroy damaging bacteria and help ease symptoms.
  • The herbs should contain significant amounts of their most beneficial compounds, such as 5% Berberine and 0.2% Allicin.
  • It should contain Caprylic acid to to promote a healthy microbiome by killing harmful bacteria and yeast and stimulating the growth of good bacteria.
  • It should contain BioPerine® or another bioavailability enhancer to optimize the results.
  • It must be 100% pure and natural, with no unnecessary ingredients that might reduce the effectiveness of the product.

Are there any side effects noted when using this product?

Our research did not uncover any negative side effects when using this product. The ingredients that are contained within the formula of Approved Science Siboprin are all natural and 100% pure. It is worth noting that, like all herbal antimicrobial supplements, when undesirable bacteria and fungus are killed, they can sometimes cause uncomfortable digestive symptoms. If this occurs, reduce the dosage to only once daily. And as with any supplement, we always recommend consulting with a doctor if you are pregnant, breastfeeding, have an existing medical condition or are taking any other medication.

What are the dosage instructions for Approved Science SIBO?

The manufacturers of this product suggest taking 2 capsules per day, 1 in the morning and one in the afternoon, before mealtime and with a glass of water. Should any discomfort be experienced, reduce to one capsule daily with food.

As with any supplement, always follow the recommended dosage instructions and do not exceed them as this poses health risks.

How long before I can see any results?

Results will vary for each person. For some, they will see changes in a few weeks, while for others it may take longer. It is different for each person. Other factors that affect results can include age, diet, and lifestyle, so it is hard to say exactly.

What you should look for are companies who offer a satisfaction guarantee. This suggests they are confident that their products will deliver the desired results, and if you don’t get the results you were hoping for you can always return the product. Approved Science Siboprin offers a great money-back guarantee and awesome feedback on how well this product works.

What price should I expect to pay?

The cost of products vary among manufacturers. Unfortunately, many are cheap, useless supplements that have no science-based evidence to back up their formulas. Some of these companies are selling their products for around $100 per bottle, which is very expensive. On average, the best supplements we found are selling between the $40-$50 price range. Often, when products appear cheaper, this is indicative of low quality or a low recommended daily serving, which will not bring the results you are looking for. Be aware. Read the labels.

Which SIBO supplement should I buy?

As each person’s experience of a product is different, it is difficult to say specifically which one is the best. That said, based on several factors, we did like Approved Science Siboprin. We found that from the 50+ products that we looked at, Approved Science Siboprin had the best quality of ingredients, potency and strength, positive consumer feedback, and excellent customer service.

How safe is it to order over the internet?

Ordering Siboprin from Approved Science is safe to do over the internet. The manufacturer utilizes the latest encryption software to protect your credit card information and does not engage in shady schemes such as ‘automatic billing’ programs like many other companies do. They also deliver very efficiently and quickly, using discreet packaging.

Why should I choose Approved Science Siboprin?

There are several reasons why we like this product including purity of ingredients, customer service, satisfaction, and effectiveness. Its formula is backed by clinical studies and we feel it values consumers’ health above and beyond the profit margins.

Approved Science Siboprin is a great product that you can depend on. It has a well-researched formula with the right ingredients in the correct potency. And if that wasn’t enough, check out the customer reviews – they say it all. It counts when there are many happy customers who are highly loyal to this brand, clearly singing the praises of this trustworthy product. We will summarize the key benefits one more time:

  • Helps to improve SIBO symptoms in a natural, effective manner.
  • Contains Micro-Sci, a unique antimicrobial complex comprising three proven herbal extracts to combat SIBO: Oregano, Barberry, and Garlic.
  • Contains an impressive 500mg Oregano extract to kill off undesirable microbes in the small intestine.
  • Contains Caprylic acid which complements and supports the herbal extracts to help restore a balanced gut microbiome.
  • Contains BioPerine® to improve the bioavailability of all the other ingredients for quicker, more effective results.
  • Targets both hydrogen- and methane-producing bacteria.
  • No preservatives, artificial colorings, hormones, or unnecessary ingredients that may dilute the efficacy of the product.

In addition to the above points, we found so many supportive consumer reviews from users who had experienced impressive results, some within as little as a week. Its daily suggested serving is the optimal potency as recommended by doctors for effectiveness and is supported by clinical research trials and studies. This manufacturer’s customer service is second to none, providing support, help, and knowledgeable advice to those who seek it. Furthermore, it offers an excellent money-back guarantee if customers are not satisfied with their results.

The Bottom Line

After some serious searching, we finally found a product that meets our standards and even exceeds some of them!

We like Approved Science due to their unique approach, exemplifying a commitment to long-term success. The company demonstrates meticulous research in ingredient selection, using pure, natural ingredients for their Siboprin formula, supported by substantial clinical data. Approved Science offers what more companies should – an effective, affordable product supported by a real concern for the health of its customers. As an added bonus, Siboprin has many happy testimonials to support our belief that this is a great product and a great company.   

What You’ll Discover:

Which SIBO supplement is the BEST BUY and comes with a great GUARANTEE!
Which formula and ingredients are the most EFFECTIVE and work the fastest?
How NOT to get ripped off! BE AWARE of poor quality and cheap products.

Top 6 Items to Consider:

  1. Ingredients
  2. Cost Per Serving
  3. Product Testing Results
  4. Company Reputation
  5. Consumer Reviews
  6. Return Policy & Satisfaction Guarantee

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